Molecular control of gonadal differentiation into the chicken embryo Into the mammalian embryo, two crucial ovarian pathways have now been defined. The initial involves the canonical ?-catenin signalling path. In this path, ovarian signalling particles R-Spondin 1 (Rspo1) and Wnt-4 activate the ?-catenin pathway within the developing feminine gonad (Fig. 2 ). Rspo1 is presently […]
